Raquel Luna

Metabolic adaptations and essentialities under hypoxia

Name of partner: Evotec , Toulouse, France.
Name of leader: Nathalie Alet

Objectives: to identify metabolic genes that are modulated or mutated in acute myeloid leukemia patient samples. Set up in vivo model(s) suitable for validation of their interest.
Expected Results: We will model a metabolic gene profile in acute myeloid leukemia and link this gene profile to patient outcome according to the treatment received. Then drugs/compounds potentially modulating the metabolic profile in a beneficial way may be tested in vivo.

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EMBO Workshop: Cancer immunometabolism

EMBO Workshop: Cancer immunometabolism

The EMBO Workshop: Cancer immunometabolism was successfully celebrated in hybrid format on the 29th of November – 1st of December …

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As part of our MSCA-ESR training on complementary skills we got to leave the wet lab to explore what happens on the other side of the bench and to learn what it means to be a scientific editor. This is our story.

Nature, Nature Medicine, Nature Reviews Cancer. Who hasn’t dreamt of publishing in one of these journals?

As part of our MSCA-ESR training on complementary skills we got to leave the wet lab to explore what happens on the other side of the bench and to learn what it means to be a scientific editor. This is our story.

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Metabolic adaptation of acute lymphoblastic leukemia to the central nervous system microenvironment is dependent on Stearoyl CoA desaturase

Metabolic adaptation of acute lymphoblastic leukemia to the central nervous system microenvironment is dependent on Stearoyl CoA desaturase

Metabolic reprogramming is a key hallmark of cancer, but less is known about metabolic plasticity of the same tumor at …

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